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KMID : 0882420090770060787
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Korean Journal of Medicine
2009 Volume.77 No. 6 p.787 ~ p.792
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A case of pneumomediastinum combined with chronic graft-versus-host disease following allogeneic hematopoietic stem cell transplantation
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Lee Ho-Sup
Shin Seong-Hoon
Kim Yang-Soo
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Abstract
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Pulmonary complications are very common after allogeneic stem cell transplantation and are sometimes serious. Late-onset noninfectious pulmonary complications of chronic graft-versus-host disease (GVHD) after allogeneic stem cell transplantation include bronchiolitis obliterans and bronchiolitis obliterans with organizing pneumonia. Especially, bronchiolitis obliterans is correlated with GVHD. If they occur simultaneously, serious pulmonary and subcutaneous complications such as pneumomediastinum, subcutaneous emphysema, and pneumothorax can occur. We present the case of a 19-year-old man who had pneumomediastinum, subcutaneous emphysema, and pneumothorax with GVHD after allogeneic stem cell transplantation.
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KEYWORD
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Pneumomediastinum, Allogeneic stem cell transplantation, Graft-versus-host disease, Bronchiolitis obliterans
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